威廉希尔willhill亚洲公司官方网站

- 姓名：叶明
- 职务：
- 职称：教授、博导
- 所属系：食品生物技术系
- 邮箱：yeming202311@163.com
- 办公地点：

个人简介
研究领域
科研项目
学术成果
荣誉奖项

先后于华东师范大学生物系毕业获理学学士学位、安徽工程大学任教、武汉大学生物化学助教进修班学习；之后于南京农业大学获理学硕士学位（导师：陈永萱教授、博导，潘迎捷研究员、博导），于山东大学获理学博士学位（导师：马桂荣教授、博导，庄文颖研究员、中国科学院院士），于第二军医大学从事博士后研究工作（导师：戚中田教授、博导）。

2004年以来，先后于威廉希尔亚洲公司任教授、硕士生导师、博士生导师、系主任、安徽省教学名师。先后主持国家及省部级纵向项目20余项、横向项目10余项，主持省、校级教学质量工程项目10余项，以第一（或通讯）作者在国内外核心期刊发表论文140余篇，其中高质量论文70余篇，近30项国家发明专利获批授权（第一发明人）；主编省规划教材两部；培养硕、博研究生（其中境外博士生2名）及博士后50余名。

（1）天然活性物质结构、功能及其作用机理
（2）新型功能食品研制及其功能评价
（3）食品生物技术及特色农产品精深加工

1.国家自然科学基金面上项目：粒毛盘菌属多糖结构、分子修饰与生物活性研究 (31470146，主持）
2.安徽省科研计划重大专项项目：植源型功能发酵乳加工关键技术研究及其产业化（15czz03106，主持）
3.国家自然科学基金面上项目：粒毛盘菌属黑色素活性筛选、分子修饰及构效关系研究 (31270060，主持)
4.科技部企业创新项目：高产粒毛盘菌菌株选育与水溶性活性黑色素产品 (12C26213403307，主持)
5.中央高校基本科研业务费专项资金项目：粒毛盘菌降脂、抗衰老多糖胶囊关键技术研究 (2012HGZY0020，主持)
6.安徽省科技攻关重点项目：瓜蒌深加工关键技术研发及新产品研发 (12010302071，主持)
7.国家自然科学基金面上项目：华东地区粒毛盘菌资源与活性物质研究（31070021，主持）
8.企业委托项目：宣酒酿造微生物菌群改良、发酵工艺及其保健功能成分研究（W2016JSKF0081 主持）
9.企业委托项目：坚果保藏及深加工关键技术研究（W2017JSKF0044，主持）
10.企业委托项目：山核桃新产品研发及其保质期研究（W2014JSKF0229，主持）
11.专利转让资金项目：从老鹰茶中提取茶多酚的方法（13-004Z，主持）
12.企业委托项目：大球盖菇功能性活性物质的开发研究（W2019JSKF0082，主持）
13.企业委托项目：山核桃特色营养成分分析及其益生菌产品开发与应用研究（W2020JSKF0758，主持）
14.企业委托项目：香榧营养成分分析及其深加工工艺（ W2021JSKF0706，主持)
15.企业委托项目：高蛋白大球盖菇培养条件研究与开发（W2023JSKF0410，主持）
16.企业委托项目：不同坚果发酵乳研制与开发（W2023JSKF0426，主持）

1.Jin M., Zhang W., Zhang X., Huang Q., Chen H., Ye M*. Characterization, chemical modification and bioactivities of a polysaccharide from Stropharia rugosoannulata. Process Biochemistry, 2023, 128: 30-39.
2.Zhang X., Liu D., Ye Z., Chen X., Chen H., Ye M*. Gastroprotective effect of the Lachnum polysaccharide and polysaccharide-dipeptide conjugates against gastric ulcer. Food and Chemical Toxicology, 2023, 174: 113661. （IF=5.572/Q1/2）
3.He Y., Liu D., Zhu C., Chen X., Ye H., Ye M*. Prevention of the Lachnum polysaccharide and its selenium derivatives on cisplatin induced acute kidney injury in mice. Bioorganic & medicinal chemistry letters, 2023: 129192.
4.He Y., Chen H., Ye Z., Zhang X., Ye H., Ye M*. Structural characterization and bioactivities of a novel polysaccharide obtained from Lachnum YM38 together with its zinc and selenium derivatives. Process Biochemistry, 2022, 122: 282-298.
5.Zong S., Ye H., Ye Z., He Y., Zhang X., Ye M*. Polysaccharides from Lachnum sp. Inhibited colitis-associated colon tumorigenesis in mice by modulating fecal microbiota and metabolites. International Immunopharmacology, 2022, 108: 108656. 90 (IF=5.6/Q1)
6.Ji J., Liu D., Ye Z., Chen W., Shaikh F., Ye M*. Lipid-lowering effect of extracellular polyphenol extracts from Lachnum singerianum in high-fat diet-fed mice. Journal of Food Processing and Preservation, 2022, 46(5).
7.Ye Z., Zhang X., Huang Q., Zhang W., Ye M*. Synergistic hepatoprotective effect of combined administration of Lachnum polysaccharide with silymarin. Bioorganic & Medicinal Chemistry Letters, 2021, 46: 128159.
8.Ye Z., Chen X., He Y., Jin M., Ye M*. Antidiabetic effects of fermented milk contained with Gardenia jasminoides water extracts on streptozotocin-induced mice. Journal of Food Processing and Preservation, 2021, 45(2).
9.Zhang W., Si G., Rao Z., Zong S., Li J., Zhang X., Gao C., Zhou P., Ye M*. Hepatoprotective ability of tetramethylpyrazine produced by Bacillus amyloliquefaciens. Systems Microbiology and Biomanufacturing, 2020. 1, 223-233.
10.Hou, G., Jin, M., Ye, Z., Zhang, X., Huang, Q., & Ye, M*. Ameliorate effects of soybean soluble polysaccharide on adenine-induced chronic renal failure in mice. International Journal of Biological Macromolecules, 2020, 149, 158-164. (IF=8.025/Q1)
11.Su, N., Ye, Z., Li, J., Yang, L., Hou, G., & Ye, M*. Effect of the addition of roselle (Hibiscus sabdariffa L.) extracts on the rheological, textural, and antioxidant activity of fermented milks. Flavour and Fragrance Journal, 2020, 35(1), 42-50.
12.Zong, S., Li, J., Ye, Z., Zhang, X., Yang, L., Chen, X., & Ye, M*. Lachnum polysaccharide suppresses S180 sarcoma by boosting anti-tumor immune responses and skewing tumor-associated macrophages toward M1 phenotype. International Journal of Biological Macromolecules, 2020, 144, 1022-1033. (IF=8.025/Q1)
13.Yang, L., He, Y., Li, J., Gao, X., Chen, T., & Ye, M*. Properties of melanin from Lachnum YM156 and its hepatoprotective effect in Cd-exposure mice. Process Biochemistry, 2020, 92, 244-251.
14.Zong, S.,Ye, Z.,Zhang, X.,Chen, H.,&Ye M*. Protective effect of Lachnum polysaccharide on dextran sulfate sodium-induced colitis in mice. Food and Function, 2020, 1, 846-859. (IF=6.058/Q1)
15.Xu, C., Chen, T., Li, J., Jin, M., & Ye, M*. The structural analysis and its hepatoprotective activity of melanin isolated from Lachnum sp. Process Biochemistry, 2020, 90, 249-256.
16.Yang, L., Yang, Q., Li, J., Hou, G., Chen, T., & Ye, M*. Nephroprotective effects of Lachnum melanin against acute kidney injury induced by cisplatin in mice. Process Biochemistry, 2020, 83, 198-205.
17.Zhang W., Li J., Rao Z., Si, G., Zhang, X., GaoZhang W., Si G., Du, H., Li, J., Ye, M.,*& Zhou, P., et al.Directional design of a starter to assemble the initial microbial fermentation community of baijiu. Food Research International, 2020, doi: 10.1016/j.foodres.2020.109255. (IF=8.1/Q1)
18.Zhang W., Li J., Rao Z., Si G., Zhang X., Gao C., Ye M*., Zhou P. Sesame flavour baijiu: a review. Journal of The Institute of Brewing, 2020, 126(3): 224-232.
19.Zong, S., Li, J., Yang, L., Huang, Q., Hou, G., Ye, Z., & Ye, M*. Mechanism of bioactive polysaccharide from Lachnum sp. acts synergistically with 5-fluorouracil against human hepatocellular carcinoma. Journal of Cellular Physiology, 2019, 234(9): 15548-15562. （IF=6.513/Q1）
20.Hou, G., Chen, X., Li, J., Ye, Z., Zong, S., & Ye, M*. Physicochemical properties, immunostimulatory activity of the Lachnum polysaccharide and polysaccharide-dipeptide conjugates. Carbohydrate Polymers, 2019, 206: 446-454. (IF=11.2/Q1)
21.Zong, S., Li, J., Yang, L., Huang, Q., Hou, G., Ye, Z., Ye, M*. Mechanism of bioactive polysaccharide from Lachnum sp. acts synergistically with 5-fluorouracil against human hepatocellular carcinoma. Journal of Cellular Physiology, 2019,1-15.
22.Hou, G., Surhio, M. M., Ye, H., Gao, X., Ye, Z., Li, J., & Ye, M*. Protective effects of a Lachnum polysaccharide against liver and kidney injury induced by lead exposure in mice. International Journal of Biological Macromolecules. 2019,124: 716-723. (IF=8.025/Q1)
23.Ye, Z., Lu, Y., Zong, S., Yang, L., Shaikh, F., Li, J., & Ye, M*. Structure, molecular modification and anti-tumor activity of melanin from Lachnum singerianum. Process Biochemistry, 2019, 76, 203-212.
24.Zhang, W., Si, G., Li, J., Ye, M.,* Feng, S., & Mei, J., et al. . Tetramethylpyrazine in Chinese sesame flavour liquor and changes during the production process. Journal of The Institute of Brewing, 2019, 125(1), 155-161.
25.Liuqing Yang, Jinglei Li, Tingting Chen, Ziyang Ye, Ming Ye*. Properties of melanin from Lachnum and its hepatoprotective effect in Cd-exposure mice. Process Biochemistry, 2019. 05.001.
26.Zhang WQ, Si, G, Rao Z, Li, J, Ye, M,*& Zhou, P, et al. High yield of tetramethylpyrazine in functional Fuqu using Bacillus amyloliquefaciens. Food Bioscience，doi:10.1016/j.fbio.2019.100435(IF＝5.2／Q1）
27.Li SL, Yang LQ, Li JL, Chen TT, Ye M*. Structure, Molecular Modification, and Anti-radiation Activity of Melanin from Lachnum YM156 on Ultraviolet B-Induced Injury in Mice. Applied Biochemistry and Biotechnology, 2019（188）:555-567.
28.Zong, S., Li, J., Yang, L., Huang, Q., Ye, Z., Hou, G., & Ye, M*. Synergistic antitumor effect of polysaccharide from Lachnum sp. in combination with cyclophosphamide in hepatocellular, Carbohydrate Polymers, 2018, 196:33-46. (IF=11.2/Q1)
29.Wang, Y., Hou, G., Li, J., Surhio, M. M., & Ye, M*.. Structure characterization, carboxymethylated and sulfated modifications, and antioxidant and hypoglycemic activities in vitro of a polysaccharide from Lachnum sp. Process Biochemistry, 2018, 72: 177-187.
30.Su NN, Li JL, Yang LQ, Hou GH, Ye M*. Hypoglycemic and hypolipidemic effects of fermented milks with added roselle ( Hibiscus sabdariffa, L.) extract. Journal of Functional Foods, 2018, 43: 234-241.(IF=5.6/Q1)
31.Su NN, Li JL, Ye ZY, Chen TT, Ye M.* Quality properties, flavor and hypoglycemia activity of, Kiwifruit-Bitter gourd, fermented milks. Food Bioscience, 2018,22: 139-145.
32.Xu, P., Yuan, R., Hou, G., Li, J., & Ye, M*. Structural Characterization and In Vitro Antitumor Activity of a Novel Exopolysaccharide from Lachnum YM130. Applied Biochemistry and Biotechnology, 2018, 185(2), 541-554.
33.Wang, Q., Liu, S., Tai, W., Li, J., Ye, M*., & Yang, L. Purification, chemical structure and antioxidant activity of active ingredient (LPT-3d) separated from Lachnum sp. Process Biochemistry, 2018, 71, 166-174.
34.Fang Shi, Jinglei Li, Liuqing Yang, Guohua Hou and Ming Ye*. Hypolipidemic effect and protection ability of liver-kidney functions of melanin from Lachnum YM226 in high-fat diet fed mice. Food & Function, 2018. DOI: 10.1039/C7FO01294B. (IF=6.058/Q1)
35.Shi, F., Li, J., Ye, Z., Yang, L., Chen, T., Chen, X., & Ye, M*. Antitumor effects of melanin from: Lachnum YM226 and its derivative in H22 tumor-bearing mice. MedChemComm, 2018, 9(6), 1059–1068.
36.Li, S., Yang, L., Li, J., Chen, T., & Ye, M*.. Structure, Molecular Modification, and Anti-radiation Activity of Melanin from Lachnum YM156 on Ultraviolet B-Induced Injury in Mice. Applied Biochemistry and Biotechnology，2018, 1-13.
37.Chen H , Hai H , Wang H , Ye M*, et al. Hydrogen-rich water mediates redox regulation of the antioxidant system, mycelial regeneration and fruiting body development in Hypsizygus marmoreus. Fungal Biology, 2018, 122(5):310.
38.Chen Hui , Zhang Jinjing , Hao Haibo , Ming Ye*. et al. Hydrogen-rich water increases postharvest quality by enhancing antioxidant capacity in Hypsizygus marmoreus. AMB Express, 2017, 7(1):221
39.Maheen Mahwish Surhio, Yufen Wang, Ping Xu, Shah Faisal, Jinglei Li, Ming Ye*. Antihyperlipidemic and hepatoprotective properties of selenium modified polysaccharide from Lachnum, sp.. International Journal of Biological Macromolecules, 2017, 99: 88-95. (IF=8.025/Q1)
40.Tianle Chen, Ping Xu, Shuai Zong, Yufen Wang, Nana Su, Ming Ye*. Purification, structural features, antioxidant and moisture-preserving activities of an exopolysaccharide from Lachnum YM262. Bioorganic & Medicinal Chemistry Letters, 2017, 27: 1225-1232.
41.Lan Li, Fang Shi, Jinglei Li, Qianli Huang, Can Xu, Liuqing Yang, Qinghua Yang, Farnaz Shaikh, Ming Ye*. Immunoregulatory effect assessment of a novel melanin and its carboxymethyl derivative. Bioorganic & Medicinal Chemistry Letters, 2017, 27(8): 1831-1834.
42.Shenglan Li, Jinglei Li, Fang Shi, Liuqing Yang and Ming Ye*. Protection effect of intracellular melanin from Lachnum YM156 and Haikunshenxi capsule combination on adenine-induced chronic renal failure in mice, MedChemComm, 2017, 8(5): 917-923.
43.Yufen Wang, Nana Su, Guohua Hou, Jinglei Li and Ming Ye*. Hypoglycemic and hypolipidemic effects of a polysaccharide from Lachnum YM240 and its derivatives in mice induced by high fat diet and low dose STZ. Medchemcomm, 2017, 8: 964-974.
44.Can Xu, Jinglei Li, Liuqing Yang, Fang Shi, Liu Yang, Ming Ye*. Antibacterial activity and a membrane damage mechanism of Lachnum YM30 melanin against Vibrio parahaemolyticus and Staphylococcus aureus, Food Control, 2017, 73: 1445-1451. (IF=6.0/Q1)
45.Ping Xu, Jinglei Li, Guohua Hou, Fang Shi, Ming Ye*. Cardioprotective effect of an exopolysaccharide from Lachnum YM130 and its derivatives on diabetic mice. Process Biochemistry, 2017, 58, 333-340.
46.Min Zhang, Nana Su, Qianli Huang, Qiang Zhang, Yufen Wang, Jinglei Li, Ming Ye*. Phosphorylation and antiaging activity of polysaccharide from Trichosanthes peel. Journal of Food and Drug Analysis, 2017, 25 (4): 976-983.
47.Lianyan Jing, Shuai Zong, Jinglei Li, Ming Ye*, Maheen Surahio, Liu Yang. Potential mechanism of protection effect of exopolysaccharide from Lachnum YM406 and its derivatives on carbon tetrachloride-induced acute liver injury in mice. Journal of Functional Foods, 2017, 36: 203-214. (IF=5.6/Q1)
48.Wenqing Zhang, Guanru Si, Ming Ye*, Shoushuai Feng, Fan Cheng, Jinglei Li, Jie Mei, Shuai Zong, Jiasheng Wang, Ping Zhou. An Efficient Assay for Simultaneous Quantification of Ethyl Carbamate and Phthalate Esters in Chinese Liquor by Gas Chromatography-Mass Spectrometry. Food Analytical Methods, 2017, 10, 3487-3495.
49.Maheen Mahwish Surhio, Yufen Wang, Shi Fang, Jinglei Li, MingYe*. Anti-fatigue activity of a Lachnum polysaccharide and its carboxymethylated derivative in mice. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 4777-4780.
50.Sheng Song, Liu Yang, Ming Ye*, Xue Chen, Fang Shi, Farnaz Shaikh. Antioxidant activity of a Lachnum YM226 melanin–iron complex and its influence on cytokine production in mice with iron deficiency anemia. Food & Function, 2016, 7(3): 1508-1514. (IF=6.058/Q1)
51.Sheng Song, Shenglan Li, Nana Su, Jinglei Li, Fang Shi and Ming Ye*. Structural characterization, molecular modification and hepatoprotective effect of melanin from Lachnum YM226 on acute alcohol-induced liver injury in mice. Food & Function, 2016, 7(8): 3617-3627.(IF=6.058/Q1)
52.Tianle Chen, Min Zhang , Jinglei Li, Maheen Mahwish Surhio, Beibei Li, Ming Ye*. Structural characterization and hypoglycemic activity of Trichosanthes peel polysaccharide. LWT-Food Science and Technology, 2016, 70: 55-62.
53.Tianle Chen, Yufen Wang, Jinglei Li, Nana Su, Maheen Mahwish Surhio, Liu Yang, Ming Ye*. Phthaloyl modification of a polysaccharide from Lachnum YM262 and immunomodulatory activity. Process Biochemistry, 2016, 51(10), 1599-1609.
54.Zhanzhan Du, Shuai Zong, Maheen Mahwish Surhio, Ping Xu, Liu Yang, Ming Ye*. Structural characterization and anti-hypoxia activity of an exopolysaccharide isolated from fermentation broth of Lachnum sp. Process Biochemistry, 2016, 51, 1290-1298.
55.Lianyan Jing, Shuai Zong, Jinglei Li, Maheen Mahwish Surhio, Ming Ye*. Purification, structural features and inhibition activity on α-glucosidase of a novel polysaccharide from Lachnum YM406. Process Biochemistry, 2016, 51(10): 1706-1713.
56.Ping Xu, Liu Yang, Ruyue Yuan, Ziyang Ye, Huiran Ye, Ming Ye*.Structure and preventive effects against ethanol-induced gastric ulcer of an expolysaccharide from Lachnum sp. International Journal of Biological Macromolecules, 2016, 86: 10-17. (IF=8.025/Q1)
57.Rong Zhang, Liu Yang, Jing Ji, Bei-bei Li, Lan Li, Ming Ye*. Physico‐chemical properties and hypoglycaemic activity of fermented milks prepared with Anemarrhena asphodeloides water extracts. Journal of the Science of Food and Agriculture, 2016, 96(2): 492-496.
58.Zhanzhan Du, Fang Shi, Dong Liu, Hongling Ye, Maheen Mahwish Surhio, Jinglei Li, Ming Ye*. Anticoagulant activity of a sulfated Lachnum polysaccharide in mice with a state of hypercoagulability. Bioorganic & Medicinal Chemistry Letters, 2016, 26: 550-5556.
59.Yunlong He, Ming Ye*, Lianyan Jing, Zhanzhan Du, Maheen Surahio, Hongmei Xu, Jie Li. Preparation, characterization and bioactivities of derivatives of an exopolysaccharide from Lachnum. Carbohydrate Polymers, 2015, 117: 788-796 (IF=11.2/Q1)
60.Yanna Wu, Ming Ye*, Zhanzhan Du, Lianyan Jing, Maheen Surahio, Liu Yang. Carboxymethylation of an exopolysaccharide from Lachnum and effect of its derivatives on experimental chronic renal failure. Carbohydrate Polymers, 2014, 114:190-195 (IF=11.2/Q1)
61.Yunlong He, Ming Ye*, Zhanzhan Du, Huiyan Wang, Yanna Wu, Liu Yang. Purification, characterization and promoting effect on wound healing of an exopolysaccharide from Lachnum YM405. Carbohydrate Polymers, 2014, 105: 169-176 (IF=11.2/Q1)
62.Ming Ye*, Geng-yi Guo, Ying Lu, Sheng Song, Hui-yan Wang, Liu Yang. Purification, structure and anti-radiation activity of melanin from Lachnum YM404. International Journal of Biological Macromolecules, 2014, 63: 170-176 (IF=8.025/Q1)
63.Ming Ye*, Geng-yi Guo, Ying Lu, Sheng Song, Hui-yan Wang, Liu Yang. Purification, structure and anti-radiation activity of melanin from fungus Lachnum YM404. International Journal of Biological Macromolecules, 2014, 63: 170-176 (IF=8.025/Q1)
64.Ming Ye*, Zhanzhan Du, Xiaojing Ma. Phosphorylation and anti-tumor activity of expopolysaccharide from Lachnum YM120. Carbohydrate Polymers, 2013, 97(2): 690-694 (IF=11.2/Q1)
65.Tao Qiu, Xiaojing Ma, Ming Ye*, Yanna Wu. Purification, structure, lipid lowering and liver protecting effects of polysaccharide from Lachnum YM281. Carbohydrate Polymers, 2013, 98(1): 922-930
66.Ming Ye*, Yan Wang, Geng-yi Guo, Yun-long He, Ying Lu, Ying-wang Ye, Qing-hua Yang, Pei-zhou Yang. Physicochemical characteristics and antioxidant activity of arginine-modified melanin from Lachnum YM-346. Food Chemistry, 2012, 135: 2490-2497 . (IF=8.8/Q1)
67.Ming Ye*, Wu-xi Chen, Tao Qiu, Ru-yue Yuan, Ying-wang Ye, Jing-min Cai. Structural characterization and anti-aging activity of extracellular polysaccharide from a strain of Lachnum sp. Food Chemistry, 2012, 132: 338-343 (IF=8.8/Q1)
68.Ming Ye*, Li Ren, Yanna Wu, Yan Wang, Yong Liu. Quality characteristics and antioxidant activity of hickory-black soybean yogurt. LWT - Food Science and Technology, 2013, 51: 314-318.
69.Ming Ye*, Dong Liu, Rong Zhang, Liu Yang, Jing Wang. Effect of hawk tea (Litsea coreana L.) on the numbers of lactic acid bacteria and flavour compounds of yoghurt. International Dairy Journal, 2012, 23: 68-71 .
70.Ming Ye*, Tao Qiu, Wei Peng, Wu-xi Chen, and Ying-wang Ye, Ying-ren Lin. Purification, characterization and hypoglycemic activity of extracellular polysaccharides from Lachnum calyculiforme. Carbohydrate Polymers, 2011, 86: 285-290 . (IF=11.2/Q1)

1. 先后获得安徽省高等学校优秀科技成果奖、安徽省自然科学奖、山东大学“品学兼优”博士研究生、威廉希尔亚洲公司优秀教学成果奖、安徽省优秀教学成果奖、威廉希尔亚洲公司论文奖、安徽省科技进步奖、安徽省教学名师奖、安徽省自然科学奖（均排名第一）。
2. 先后任安徽省微生物学会常务理事，安徽省食用菌学会理事，安徽省食品质量安全委员会委员，《微生物学杂志》编委，《生物学杂志》编委，《微生物前沿》编委，《食品研究与开发》编委，《中国现代医生》编委，承担十几个中外期刊审稿工作；国家科技部863项目评审专家，国家科技进步奖项目评审专家，教育部高等学校优秀科技成果奖评审专家，国家精品课程项目评审专家，国家自然科学基金项目评审专家。

职务：		职称：	教授、博导
所属系：	食品生物技术系	邮箱：	yeming202311@163.com
办公地点：		学术成果	<br>1.Jin M., Zhang W., Zhang X., Huang Q., Chen H., Ye M. Characterization, chemical modification and bioactivities of a polysaccharide from Stropharia rugosoannulata. Process Biochemistry, 2023, 128: 30-39. <br>2.Zhang X., Liu D., Ye Z., Chen X., Chen H., Ye M. Gastroprotective effect of the Lachnum polysaccharide and polysaccharide-dipeptide conjugates against gastric ulcer. Food and Chemical Toxicology, 2023, 174: 113661. （IF=5.572/Q1/2） <br>3.He Y., Liu D., Zhu C., Chen X., Ye H., Ye M. Prevention of the Lachnum polysaccharide and its selenium derivatives on cisplatin induced acute kidney injury in mice. Bioorganic & medicinal chemistry letters, 2023: 129192. <br>4.He Y., Chen H., Ye Z., Zhang X., Ye H., Ye M. Structural characterization and bioactivities of a novel polysaccharide obtained from Lachnum YM38 together with its zinc and selenium derivatives. Process Biochemistry, 2022, 122: 282-298. <br>5.Zong S., Ye H., Ye Z., He Y., Zhang X., Ye M. Polysaccharides from Lachnum sp. Inhibited colitis-associated colon tumorigenesis in mice by modulating fecal microbiota and metabolites. International Immunopharmacology, 2022, 108: 108656. 90 (IF=5.6/Q1) <br>6.Ji J., Liu D., Ye Z., Chen W., Shaikh F., Ye M. Lipid-lowering effect of extracellular polyphenol extracts from Lachnum singerianum in high-fat diet-fed mice. Journal of Food Processing and Preservation, 2022, 46(5). <br>7.Ye Z., Zhang X., Huang Q., Zhang W., Ye M. Synergistic hepatoprotective effect of combined administration of Lachnum polysaccharide with silymarin. Bioorganic & Medicinal Chemistry Letters, 2021, 46: 128159. <br>8.Ye Z., Chen X., He Y., Jin M., Ye M. Antidiabetic effects of fermented milk contained with Gardenia jasminoides water extracts on streptozotocin-induced mice. Journal of Food Processing and Preservation, 2021, 45(2). <br>9.Zhang W., Si G., Rao Z., Zong S., Li J., Zhang X., Gao C., Zhou P., Ye M. Hepatoprotective ability of tetramethylpyrazine produced by Bacillus amyloliquefaciens. Systems Microbiology and Biomanufacturing, 2020. 1, 223-233. <br>10.Hou, G., Jin, M., Ye, Z., Zhang, X., Huang, Q., & Ye, M. Ameliorate effects of soybean soluble polysaccharide on adenine-induced chronic renal failure in mice. International Journal of Biological Macromolecules, 2020, 149, 158-164. (IF=8.025/Q1) <br>11.Su, N., Ye, Z., Li, J., Yang, L., Hou, G., & Ye, M. Effect of the addition of roselle (Hibiscus sabdariffa L.) extracts on the rheological, textural, and antioxidant activity of fermented milks. Flavour and Fragrance Journal, 2020, 35(1), 42-50. <br>12.Zong, S., Li, J., Ye, Z., Zhang, X., Yang, L., Chen, X., & Ye, M. Lachnum polysaccharide suppresses S180 sarcoma by boosting anti-tumor immune responses and skewing tumor-associated macrophages toward M1 phenotype. International Journal of Biological Macromolecules, 2020, 144, 1022-1033. (IF=8.025/Q1) <br>13.Yang, L., He, Y., Li, J., Gao, X., Chen, T., & Ye, M. Properties of melanin from Lachnum YM156 and its hepatoprotective effect in Cd-exposure mice. Process Biochemistry, 2020, 92, 244-251. <br>14.Zong, S.,Ye, Z.,Zhang, X.,Chen, H.,&Ye M. Protective effect of Lachnum polysaccharide on dextran sulfate sodium-induced colitis in mice. Food and Function, 2020, 1, 846-859. (IF=6.058/Q1) <br>15.Xu, C., Chen, T., Li, J., Jin, M., & Ye, M. The structural analysis and its hepatoprotective activity of melanin isolated from Lachnum sp. Process Biochemistry, 2020, 90, 249-256. <br>16.Yang, L., Yang, Q., Li, J., Hou, G., Chen, T., & Ye, M. Nephroprotective effects of Lachnum melanin against acute kidney injury induced by cisplatin in mice. Process Biochemistry, 2020, 83, 198-205. <br>17.Zhang W., Li J., Rao Z., Si, G., Zhang, X., GaoZhang W., Si G., Du, H., Li, J., Ye, M.,& Zhou, P., et al.Directional design of a starter to assemble the initial microbial fermentation community of baijiu. Food Research International, 2020, doi: 10.1016/j.foodres.2020.109255. (IF=8.1/Q1) <br>18.Zhang W., Li J., Rao Z., Si G., Zhang X., Gao C., Ye M., Zhou P. Sesame flavour baijiu: a review. Journal of The Institute of Brewing, 2020, 126(3): 224-232. <br>19.Zong, S., Li, J., Yang, L., Huang, Q., Hou, G., Ye, Z., & Ye, M. Mechanism of bioactive polysaccharide from Lachnum sp. acts synergistically with 5-fluorouracil against human hepatocellular carcinoma. Journal of Cellular Physiology, 2019, 234(9): 15548-15562. （IF=6.513/Q1） <br>20.Hou, G., Chen, X., Li, J., Ye, Z., Zong, S., & Ye, M. Physicochemical properties, immunostimulatory activity of the Lachnum polysaccharide and polysaccharide-dipeptide conjugates. Carbohydrate Polymers, 2019, 206: 446-454. (IF=11.2/Q1) <br>21.Zong, S., Li, J., Yang, L., Huang, Q., Hou, G., Ye, Z., Ye, M. Mechanism of bioactive polysaccharide from Lachnum sp. acts synergistically with 5-fluorouracil against human hepatocellular carcinoma. Journal of Cellular Physiology, 2019,1-15. <br>22.Hou, G., Surhio, M. M., Ye, H., Gao, X., Ye, Z., Li, J., & Ye, M. Protective effects of a Lachnum polysaccharide against liver and kidney injury induced by lead exposure in mice. International Journal of Biological Macromolecules. 2019,124: 716-723. (IF=8.025/Q1) <br>23.Ye, Z., Lu, Y., Zong, S., Yang, L., Shaikh, F., Li, J., & Ye, M. Structure, molecular modification and anti-tumor activity of melanin from Lachnum singerianum. Process Biochemistry, 2019, 76, 203-212. <br>24.Zhang, W., Si, G., Li, J., Ye, M., Feng, S., & Mei, J., et al. . Tetramethylpyrazine in Chinese sesame flavour liquor and changes during the production process. Journal of The Institute of Brewing, 2019, 125(1), 155-161. <br>25.Liuqing Yang, Jinglei Li, Tingting Chen, Ziyang Ye, Ming Ye. Properties of melanin from Lachnum and its hepatoprotective effect in Cd-exposure mice. Process Biochemistry, 2019. 05.001. <br>26.Zhang WQ, Si, G, Rao Z, Li, J, Ye, M,& Zhou, P, et al. High yield of tetramethylpyrazine in functional Fuqu using Bacillus amyloliquefaciens. Food Bioscience，doi:10.1016/j.fbio.2019.100435(IF＝5.2／Q1） <br>27.Li SL, Yang LQ, Li JL, Chen TT, Ye M. Structure, Molecular Modification, and Anti-radiation Activity of Melanin from Lachnum YM156 on Ultraviolet B-Induced Injury in Mice. Applied Biochemistry and Biotechnology, 2019（188）:555-567. <br>28.Zong, S., Li, J., Yang, L., Huang, Q., Ye, Z., Hou, G., & Ye, M. Synergistic antitumor effect of polysaccharide from Lachnum sp. in combination with cyclophosphamide in hepatocellular, Carbohydrate Polymers, 2018, 196:33-46. (IF=11.2/Q1) <br>29.Wang, Y., Hou, G., Li, J., Surhio, M. M., & Ye, M.. Structure characterization, carboxymethylated and sulfated modifications, and antioxidant and hypoglycemic activities in vitro of a polysaccharide from Lachnum sp. Process Biochemistry, 2018, 72: 177-187. <br>30.Su NN, Li JL, Yang LQ, Hou GH, Ye M. Hypoglycemic and hypolipidemic effects of fermented milks with added roselle ( Hibiscus sabdariffa, L.) extract. Journal of Functional Foods, 2018, 43: 234-241.(IF=5.6/Q1) <br>31.Su NN, Li JL, Ye ZY, Chen TT, Ye M.* Quality properties, flavor and hypoglycemia activity of, Kiwifruit-Bitter gourd, fermented milks. Food Bioscience, 2018,22: 139-145. <br>32.Xu, P., Yuan, R., Hou, G., Li, J., & Ye, M. Structural Characterization and In Vitro Antitumor Activity of a Novel Exopolysaccharide from Lachnum YM130. Applied Biochemistry and Biotechnology, 2018, 185(2), 541-554. <br>33.Wang, Q., Liu, S., Tai, W., Li, J., Ye, M., & Yang, L. Purification, chemical structure and antioxidant activity of active ingredient (LPT-3d) separated from Lachnum sp. Process Biochemistry, 2018, 71, 166-174. <br>34.Fang Shi, Jinglei Li, Liuqing Yang, Guohua Hou and Ming Ye. Hypolipidemic effect and protection ability of liver-kidney functions of melanin from Lachnum YM226 in high-fat diet fed mice. Food & Function, 2018. DOI: 10.1039/C7FO01294B. (IF=6.058/Q1) <br>35.Shi, F., Li, J., Ye, Z., Yang, L., Chen, T., Chen, X., & Ye, M. Antitumor effects of melanin from: Lachnum YM226 and its derivative in H22 tumor-bearing mice. MedChemComm, 2018, 9(6), 1059–1068. <br>36.Li, S., Yang, L., Li, J., Chen, T., & Ye, M.. Structure, Molecular Modification, and Anti-radiation Activity of Melanin from Lachnum YM156 on Ultraviolet B-Induced Injury in Mice. Applied Biochemistry and Biotechnology，2018, 1-13. <br>37.Chen H , Hai H , Wang H , Ye M, et al. Hydrogen-rich water mediates redox regulation of the antioxidant system, mycelial regeneration and fruiting body development in Hypsizygus marmoreus. Fungal Biology, 2018, 122(5):310. <br>38.Chen Hui , Zhang Jinjing , Hao Haibo , Ming Ye. et al. Hydrogen-rich water increases postharvest quality by enhancing antioxidant capacity in Hypsizygus marmoreus. AMB Express, 2017, 7(1):221 <br>39.Maheen Mahwish Surhio, Yufen Wang, Ping Xu, Shah Faisal, Jinglei Li, Ming Ye. Antihyperlipidemic and hepatoprotective properties of selenium modified polysaccharide from Lachnum, sp.. International Journal of Biological Macromolecules, 2017, 99: 88-95. (IF=8.025/Q1) <br>40.Tianle Chen, Ping Xu, Shuai Zong, Yufen Wang, Nana Su, Ming Ye. Purification, structural features, antioxidant and moisture-preserving activities of an exopolysaccharide from Lachnum YM262. Bioorganic & Medicinal Chemistry Letters, 2017, 27: 1225-1232. <br>41.Lan Li, Fang Shi, Jinglei Li, Qianli Huang, Can Xu, Liuqing Yang, Qinghua Yang, Farnaz Shaikh, Ming Ye. Immunoregulatory effect assessment of a novel melanin and its carboxymethyl derivative. Bioorganic & Medicinal Chemistry Letters, 2017, 27(8): 1831-1834. <br>42.Shenglan Li, Jinglei Li, Fang Shi, Liuqing Yang and Ming Ye. Protection effect of intracellular melanin from Lachnum YM156 and Haikunshenxi capsule combination on adenine-induced chronic renal failure in mice, MedChemComm, 2017, 8(5): 917-923. <br>43.Yufen Wang, Nana Su, Guohua Hou, Jinglei Li and Ming Ye. Hypoglycemic and hypolipidemic effects of a polysaccharide from Lachnum YM240 and its derivatives in mice induced by high fat diet and low dose STZ. Medchemcomm, 2017, 8: 964-974. <br>44.Can Xu, Jinglei Li, Liuqing Yang, Fang Shi, Liu Yang, Ming Ye. Antibacterial activity and a membrane damage mechanism of Lachnum YM30 melanin against Vibrio parahaemolyticus and Staphylococcus aureus, Food Control, 2017, 73: 1445-1451. (IF=6.0/Q1) <br>45.Ping Xu, Jinglei Li, Guohua Hou, Fang Shi, Ming Ye. Cardioprotective effect of an exopolysaccharide from Lachnum YM130 and its derivatives on diabetic mice. Process Biochemistry, 2017, 58, 333-340. <br>46.Min Zhang, Nana Su, Qianli Huang, Qiang Zhang, Yufen Wang, Jinglei Li, Ming Ye. Phosphorylation and antiaging activity of polysaccharide from Trichosanthes peel. Journal of Food and Drug Analysis, 2017, 25 (4): 976-983. <br>47.Lianyan Jing, Shuai Zong, Jinglei Li, Ming Ye, Maheen Surahio, Liu Yang. Potential mechanism of protection effect of exopolysaccharide from Lachnum YM406 and its derivatives on carbon tetrachloride-induced acute liver injury in mice. Journal of Functional Foods, 2017, 36: 203-214. (IF=5.6/Q1) <br>48.Wenqing Zhang, Guanru Si, Ming Ye, Shoushuai Feng, Fan Cheng, Jinglei Li, Jie Mei, Shuai Zong, Jiasheng Wang, Ping Zhou. An Efficient Assay for Simultaneous Quantification of Ethyl Carbamate and Phthalate Esters in Chinese Liquor by Gas Chromatography-Mass Spectrometry. Food Analytical Methods, 2017, 10, 3487-3495. <br>49.Maheen Mahwish Surhio, Yufen Wang, Shi Fang, Jinglei Li, MingYe. Anti-fatigue activity of a Lachnum polysaccharide and its carboxymethylated derivative in mice. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 4777-4780. <br>50.Sheng Song, Liu Yang, Ming Ye, Xue Chen, Fang Shi, Farnaz Shaikh. Antioxidant activity of a Lachnum YM226 melanin–iron complex and its influence on cytokine production in mice with iron deficiency anemia. Food & Function, 2016, 7(3): 1508-1514. (IF=6.058/Q1) <br>51.Sheng Song, Shenglan Li, Nana Su, Jinglei Li, Fang Shi and Ming Ye. Structural characterization, molecular modification and hepatoprotective effect of melanin from Lachnum YM226 on acute alcohol-induced liver injury in mice. Food & Function, 2016, 7(8): 3617-3627.(IF=6.058/Q1) <br>52.Tianle Chen, Min Zhang , Jinglei Li, Maheen Mahwish Surhio, Beibei Li, Ming Ye. Structural characterization and hypoglycemic activity of Trichosanthes peel polysaccharide. LWT-Food Science and Technology, 2016, 70: 55-62. <br>53.Tianle Chen, Yufen Wang, Jinglei Li, Nana Su, Maheen Mahwish Surhio, Liu Yang, Ming Ye. Phthaloyl modification of a polysaccharide from Lachnum YM262 and immunomodulatory activity. Process Biochemistry, 2016, 51(10), 1599-1609. <br>54.Zhanzhan Du, Shuai Zong, Maheen Mahwish Surhio, Ping Xu, Liu Yang, Ming Ye. Structural characterization and anti-hypoxia activity of an exopolysaccharide isolated from fermentation broth of Lachnum sp. Process Biochemistry, 2016, 51, 1290-1298. <br>55.Lianyan Jing, Shuai Zong, Jinglei Li, Maheen Mahwish Surhio, Ming Ye. Purification, structural features and inhibition activity on α-glucosidase of a novel polysaccharide from Lachnum YM406. Process Biochemistry, 2016, 51(10): 1706-1713. <br>56.Ping Xu, Liu Yang, Ruyue Yuan, Ziyang Ye, Huiran Ye, Ming Ye.Structure and preventive effects against ethanol-induced gastric ulcer of an expolysaccharide from Lachnum sp. International Journal of Biological Macromolecules, 2016, 86: 10-17. (IF=8.025/Q1) <br>57.Rong Zhang, Liu Yang, Jing Ji, Bei-bei Li, Lan Li, Ming Ye. Physico‐chemical properties and hypoglycaemic activity of fermented milks prepared with Anemarrhena asphodeloides water extracts. Journal of the Science of Food and Agriculture, 2016, 96(2): 492-496. <br>58.Zhanzhan Du, Fang Shi, Dong Liu, Hongling Ye, Maheen Mahwish Surhio, Jinglei Li, Ming Ye. Anticoagulant activity of a sulfated Lachnum polysaccharide in mice with a state of hypercoagulability. Bioorganic & Medicinal Chemistry Letters, 2016, 26: 550-5556. <br>59.Yunlong He, Ming Ye, Lianyan Jing, Zhanzhan Du, Maheen Surahio, Hongmei Xu, Jie Li. Preparation, characterization and bioactivities of derivatives of an exopolysaccharide from Lachnum. Carbohydrate Polymers, 2015, 117: 788-796 (IF=11.2/Q1) <br>60.Yanna Wu, Ming Ye, Zhanzhan Du, Lianyan Jing, Maheen Surahio, Liu Yang. Carboxymethylation of an exopolysaccharide from Lachnum and effect of its derivatives on experimental chronic renal failure. Carbohydrate Polymers, 2014, 114:190-195 (IF=11.2/Q1) <br>61.Yunlong He, Ming Ye, Zhanzhan Du, Huiyan Wang, Yanna Wu, Liu Yang. Purification, characterization and promoting effect on wound healing of an exopolysaccharide from Lachnum YM405. Carbohydrate Polymers, 2014, 105: 169-176 (IF=11.2/Q1) <br>62.Ming Ye, Geng-yi Guo, Ying Lu, Sheng Song, Hui-yan Wang, Liu Yang. Purification, structure and anti-radiation activity of melanin from Lachnum YM404. International Journal of Biological Macromolecules, 2014, 63: 170-176 (IF=8.025/Q1) <br>63.Ming Ye, Geng-yi Guo, Ying Lu, Sheng Song, Hui-yan Wang, Liu Yang. Purification, structure and anti-radiation activity of melanin from fungus Lachnum YM404. International Journal of Biological Macromolecules, 2014, 63: 170-176 (IF=8.025/Q1) <br>64.Ming Ye, Zhanzhan Du, Xiaojing Ma. Phosphorylation and anti-tumor activity of expopolysaccharide from Lachnum YM120. Carbohydrate Polymers, 2013, 97(2): 690-694 (IF=11.2/Q1) <br>65.Tao Qiu, Xiaojing Ma, Ming Ye, Yanna Wu. Purification, structure, lipid lowering and liver protecting effects of polysaccharide from Lachnum YM281. Carbohydrate Polymers, 2013, 98(1): 922-930 <br>66.Ming Ye, Yan Wang, Geng-yi Guo, Yun-long He, Ying Lu, Ying-wang Ye, Qing-hua Yang, Pei-zhou Yang. Physicochemical characteristics and antioxidant activity of arginine-modified melanin from Lachnum YM-346. Food Chemistry, 2012, 135: 2490-2497 . (IF=8.8/Q1) <br>67.Ming Ye, Wu-xi Chen, Tao Qiu, Ru-yue Yuan, Ying-wang Ye, Jing-min Cai. Structural characterization and anti-aging activity of extracellular polysaccharide from a strain of Lachnum sp. Food Chemistry, 2012, 132: 338-343 (IF=8.8/Q1) <br>68.Ming Ye, Li Ren, Yanna Wu, Yan Wang, Yong Liu. Quality characteristics and antioxidant activity of hickory-black soybean yogurt. LWT - Food Science and Technology, 2013, 51: 314-318. <br>69.Ming Ye, Dong Liu, Rong Zhang, Liu Yang, Jing Wang. Effect of hawk tea (Litsea coreana L.) on the numbers of lactic acid bacteria and flavour compounds of yoghurt. International Dairy Journal, 2012, 23: 68-71 . <br>70.Ming Ye*, Tao Qiu, Wei Peng, Wu-xi Chen, and Ying-wang Ye, Ying-ren Lin. Purification, characterization and hypoglycemic activity of extracellular polysaccharides from Lachnum calyculiforme. Carbohydrate Polymers, 2011, 86: 285-290 . (IF=11.2/Q1)
研究领域	<br>（1）天然活性物质结构、功能及其作用机理 <br>（2）新型功能食品研制及其功能评价 <br>（3）食品生物技术及特色农产品精深加工	科研项目	<br>1.国家自然科学基金面上项目：粒毛盘菌属多糖结构、分子修饰与生物活性研究 (31470146，主持） <br>2.安徽省科研计划重大专项项目：植源型功能发酵乳加工关键技术研究及其产业化（15czz03106，主持） <br>3.国家自然科学基金面上项目：粒毛盘菌属黑色素活性筛选、分子修饰及构效关系研究 (31270060，主持) <br>4.科技部企业创新项目：高产粒毛盘菌菌株选育与水溶性活性黑色素产品 (12C26213403307，主持) <br>5.中央高校基本科研业务费专项资金项目：粒毛盘菌降脂、抗衰老多糖胶囊关键技术研究 (2012HGZY0020，主持) <br>6.安徽省科技攻关重点项目：瓜蒌深加工关键技术研发及新产品研发 (12010302071，主持) <br>7.国家自然科学基金面上项目：华东地区粒毛盘菌资源与活性物质研究（31070021，主持） <br>8.企业委托项目：宣酒酿造微生物菌群改良、发酵工艺及其保健功能成分研究（W2016JSKF0081 主持） <br>9.企业委托项目：坚果保藏及深加工关键技术研究（W2017JSKF0044，主持） <br>10.企业委托项目：山核桃新产品研发及其保质期研究（W2014JSKF0229，主持） <br>11.专利转让资金项目：从老鹰茶中提取茶多酚的方法（13-004Z，主持） <br>12.企业委托项目：大球盖菇功能性活性物质的开发研究（W2019JSKF0082，主持） <br>13.企业委托项目：山核桃特色营养成分分析及其益生菌产品开发与应用研究（W2020JSKF0758，主持） <br>14.企业委托项目：香榧营养成分分析及其深加工工艺（ W2021JSKF0706，主持) <br>15.企业委托项目：高蛋白大球盖菇培养条件研究与开发（W2023JSKF0410，主持） <br>16.企业委托项目：不同坚果发酵乳研制与开发（W2023JSKF0426，主持）
荣誉奖项	<br>1. 先后获得安徽省高等学校优秀科技成果奖、安徽省自然科学奖、山东大学“品学兼优”博士研究生、威廉希尔亚洲公司优秀教学成果奖、安徽省优秀教学成果奖、威廉希尔亚洲公司论文奖、安徽省科技进步奖、安徽省教学名师奖、安徽省自然科学奖（均排名第一）。 <br>2. 先后任安徽省微生物学会常务理事，安徽省食用菌学会理事，安徽省食品质量安全委员会委员，《微生物学杂志》编委，《生物学杂志》编委，《微生物前沿》编委，《食品研究与开发》编委，《中国现代医生》编委，承担十几个中外期刊审稿工作；国家科技部863项目评审专家，国家科技进步奖项目评审专家，教育部高等学校优秀科技成果奖评审专家，国家精品课程项目评审专家，国家自然科学基金项目评审专家。