食品生物技术系

（1）果蔬采后品质形成机制；
（2）农产品采后贮藏生物学；
（3）H2S信号转导。

1.国家自然科学基金面上项目，H2S巯基化修饰TPL2抑制ERF4-TPL2-HDA9复合体的形成调控梨果皮花青苷积累的分子机制(32272682), 2023.1-2026.12，在研，直接经费54万，主持。
2.国家自然科学基金青年项目, ERF4与ERF3竞争性结合MYB114-bHLH3抑制红皮梨花青苷合成的作用机制(31901993), 2020.1-2022.12，结题，直接经费25万，主持。
3.安徽省自然科学基金面上项目, 转录因子HY5调控红皮梨花青苷转运的功能及作用机制(1908085MC72), 2019.07 -2022.06，结题，经费10万，主持。
4.安徽省科技厅，基于发酵过程高效分解生物降解塑料的畜禽粪肥开发与应用研究（2022i01020018），项目总经费：80万元，在研，校内主持。

一、发表论文情况（第一或通讯作者*）：

1.HY Sun, KD Hu, SW Wei, GF Yao*, H Zhang* ETHYLENE RESPONSE FACTOR4.1/4.2 negatively regulates anthocyanin biosynthesis in red-skinned pears, Plant Physiol., 2023, https://doi.org/10.1093/plphys/kiad068.

2.GF Yao†,*, SS Gou†, TY Zhong†, SW Wei, X An, HY Sun, C Sun, KD Hu, H Zhang* Persulfidation of MYB10 interferes MYB10-MYB73-MYB6 complex thereby inhibiting anthocyanin synthesis in red-skinned pear，Plant Physiol.,2023.https://doi.org/10.1093/plphys/kiad100

3.C Sun†, GF Yao†,*, LX Li, TT Li, YQ Zhao, KD Hu, C H, Zhang, H Zhang* Persulfidation of the E3 ligase BRG3 delays tomato ripening by reducing ubiquitination of the repressor WRKY71 involved in CAS1 transcription. Plant Physiol., 2023, https://doi.org/10.1093/plphys/kiad070.

4.C. Sun†, W.-W. Zhang†, H.-Y. Qu, L.-F. Yan, L.-X. Li, Y.-Q. Zhao, H.-Q. Yang, H. Zhang, G.-F. Yao*, K.-D. Hu* Comparative physiological and transcriptomic analysis reveal MdWRKY75 associated with sucrose accumulation in postharvest ‘Honeycrisp’ apples with bitter pit. BMC Plant Biol. 2022, 22:71.

5.H.-Y. Sun†, W.-W. Zhang†, H.-Y. Qu, S.-S. Gou, L.-X. Li, H.-H. Song, H.-Q. Yang, W.-J. Li, H. Zhang, K.-D. Hu*, G.-F. Yao*. Transcriptomics reveals the ERF2-BHLH2-CML5 module responses to H2S and ROS in postharvest calcium deficiency apples. Int. J. Mol. Sci. 2021, 22,13013.

6.Z.-Y. Ning†, K.D. Hu†, Z.L. Zhou†, D.L. Zhao, J. Tang, H. Wang, L.X. Li, C. Ding, X.Y. Chen, G.F. Yao* and H. Zhang*. IbERF71, with IbMYB340 and IbbHLH2, coregulates anthocyanin accumulation by binding to the IbANS1 promoter in purple-fleshed sweet potato (Ipomoea batatas L.). Plant Cell Reports, 2021, 40:157–169.

7.L.-X. Li, Z.-Z. Wei, Z.-L. Zhou, D.-L. Zhao, J. Tang, F. Yang, Y.-H. Lia, X.-Y. Chen, Z. Han, G.-F. Yao**, K.-D. Hu***, H. Zhang* A single amino acid mutant in the EAR motif of IbMYB44.2 reduced the inhibition of anthocyanin accumulation in the purple-fleshed sweetpotato. Plant Physiol. Bioch.,167 (2021) 410–419.

8.H.-H. Song†, Z.-L. Zhou†, D.-L. Zhao†, J. Tang, Y.-H. Li, Z. Han, X.-Y. Chen, K.-D. Hu*, G.-F. Yao*, H. Zhang* Storage property is positively correlated with antioxidant capacity in different sweet potato cultivars. Front. Plant Sci. (2021) 12:696142.

9.T.‑Y. Zhong†, G.‑F. Yao†, S.-S. Wang, T.-T. Li, K.-K. Sun, J. Tang, Z.-Q. Huang, F. Yang, Y.-H. Li, X.-Y. Chen, L.-Y. Hu, H. Zhang, K.-D. Hu. Hydrogen sulfide maintains good nutrition and delays postharvest senescence in postharvest tomato fruits by regulating antioxidative metabolism. J. Plant Growth Regul. (2021) 40, 2548–2559.

10.Z-Z. Wei†, K-D Hu†, D-L Zhao†, J. Tang, Z.-Q Huang, P. Jin, Y.-H. Li, Z Han, L.-Y. Hu, G-F. Yao*, H. Zhang*. MYB44 competitively inhibits the formation of the MYB340-bHLH2-NAC56 complex to regulate anthocyanin biosynthesis in purple-fleshed sweet potato. BMC Plant Biol. 2020, 20:258.
11.C. Li#, J. Wu#, K.-D. Hu#, S.-W. Wei, H.-Y. Sun, L.-Y. Hu, Z. Han, G.-F. Yao*, H. Zhang*. PyWRKY26 and PybHLH3 cotargeted the PyMYB114 promoter to regulate anthocyanin biosynthesis and transport in red-skinned pears. Hortic. Res., 2020, 7(37):1-12.

12.G.-F. Yao†, C. Li†, K.-K. Sun†, J. Tang, Z.-Q. Huang, F. Yang, G.-G. Huang, L.-Y. Hu, P. Jin, K.-D. Hu*, H. Zhang* Hydrogen sulfide maintained the good appearance and nutrition in post-harvest tomato fruits by antagonizing the effect of ethylene. Front. Plant Sci. 2020, 11:584.

13.S.Q. Wang#, J. Tang#, K.D. Hu#, Z.Q. Huang, F. Yang, H.Y. Zhang, L.Y. Hu, Y.H. Li, G.F. Yao*, H. Zhang*. Antioxidative system in sweet potato root is activated by low temperature storage. Journal of the Science of Food and Agriculture. 2019, 99(8):3824-3833.

14.K.D. Hu#, X.Y. Zhang#, S.S. Wang#, J. Tang, F. Yang, Z.Q. Huang, J.Y. Deng, S.Y. Liu, S. J. Zhao, L.Y. Hu, G.F. Yao*, H. Zhang*. Hydrogen sulfide inhibits fruit softening by regulating ethylene synthesis and signaling pathway in tomato (Solanum lycopersicum). HortScience. 2019, 54 (10):1824–1830.

四、国家专利申请情况：
1.姚改芳，胡康棣，张华，魏曾正，唐君，胡兰英，钟庭颖，孙红叶，孙忱. 一种调节花青苷合成的IbMYB44基因及其重组表达载体与应用，专利号：2019107248674，授权日：2022.05.03

2.姚改芳，张华，吴俊，胡康棣，李闯，钟庭颍，孙红叶，荣誉磊，赵玉琪. 一种促进花青苷合成的PyWRKY26基因及其重组表达载体与应用，专利号：2019113859463，授权日：2022.05.03

3.姚改芳，张华，孙红叶，胡康棣，颜龙飞，安欣.一种抑制花青苷生物合成的梨转录因子PyERF4.2基因及其重组表达载体与应用，申请号：2022108276387，申请日：2022.7.11

4.姚改芳，苟莎莎，张华，胡康棣，张从合，安欣，钟婷颖，张敏. 一种促进花青苷合成的PyMYB73基因及其重组表达载体与应用. 申请日：2022.12.20, 申请号：2023100059451.

5.姚改芳，苟莎莎，张华，张从合，胡康棣，钟婷颖，孙忱，孙红叶，赵玉琪一种抑制花青苷合成的PyMYB6基因及其重组表达载体与应用. 申请日：2022.12.20, 申请号：2023100059875.

6.张华，姚改芳，胡康棣，宁致远，唐君，邓敬宇，孙红叶，钟庭颖，孙忱. 一种促进花青苷合成的ItfERF71a基因及其重组表达载体与应用，专利号：2019107240028，授权日：2022.0503

7.张华，姚改芳，胡康棣，魏曾正，唐君，胡兰英，李延红，陈晓燕，钟庭颖，孙红叶. 一种促进花青苷合成的IbNAC56基因及其应用，专利号：ZL 201910724870.6，授权日：2022.05.03

8.吴俊；姚改芳；明美玲; 张绍铃; 谷超; 常耀军; 汪润泽; 殷豪；梨转录因子PyMYB114及其重组表达载体和应用, 2017.6.23, 中国, CN201710485838

9.吴俊；姚改芳；张绍铃; 明美玲; 谷超; 汪润泽; 杨广艳; 刘海楠；梨转录因子PyERF3及其重组表达载体和应用, 2017.08.31, 中国, CN201710768517

10.吴俊; 姚改芳; 张绍铃; 杨广艳; 李甲明; 汪润泽; 齐开杰; 梨果实花青苷转运相关PyGSTf12基因及其重组表达载体和应用, 2019.01.04, 201910008908.X

11.吴俊；姚改芳；张绍铃；杨广艳；张明月；汪润泽；谢智华；梨转录因子PyHY5及其重组表达载体和应用, 2019.01.04，201910008926.8

12.姚改芳，张华，孙忱，胡康棣，孙红叶，苟莎莎，安欣.一种抑制番茄果实成熟的基因SlWRKY71及其调控方法，申请号：202211135311X, 申请日：2022.8.29

13.张华，姚改芳，孙红叶，胡康棣，苟沙沙，肖钰薇. 一种抑制花青苷生物合成的梨转录因子PyERF4.1基因及其重组表达载体，申请号：2022108276230，申请日：2022.7.11

14.张华，孙忱，姚改芳，胡康棣，孙红叶，颜龙飞，肖钰薇. 一种促进番茄果实成熟的基因SlCAS1及其调控方法，申请号：2022111353054，申请日： 2022.8.29

15.张华，孙红叶，姚改芳，苟莎莎，张从合，胡康棣，钟婷颖，孙忱. 一种巯基化修饰位点突变促进花青苷合成的PyMYB10基因及其重组表达载体与应用.申请日：2022.12.20, 申请号：2023100059593.